Mar 09
Following study has qualitative aspect. Researchers took qualitative interviews of Ca OPX patients and matched group. I read abstract so far, and I believe that this study might be suffering from many flaws. one important is matching process. Since smoking is strong predictor of OPX ca, in such case, how precisely other varibales like eating habits were controlled in the analysis is matter of interest as well concerns. I am wondering how dairy products offer protection against OPX ca. Need to do more literature search.
Toporcov et al (2012) Consumption of animal-derived foods and mouth and oropharyngeal cancer].
Brasil. toporcov@usp.br
OBJECTIVE:Evaluate the relationship between animal-derived foods and mouth and oropharyngeal cancer.METHODS:Hospital-based case-control study matched by sex and age (± 5 years) with data collected between July of 2006 and June of 2008. The sample contained 296 patients with mouth and oropharyngeal cancer and 296 patients without a cancer history who were treated in four hospitals in the City of São Paulo, State of São Paulo, Brazil. A semistructured questionnaire was administered to collect data regarding socioeconomic condition and harmful habits (tobacco and alcoholic beverage consumption). To assess eating habits, a qualitative questionnaire that asked about the frequency of food consumption was used. The analysis was rendered by means of multivariate logistic regression models that considered the existing hierarchy among the characteristics studied.RESULTS:
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Among foods of animal origin, frequent consumption of beef (OR = 2.73; CI95% = 1.27-5.87; P < 0.001),
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bacon (OR = 2.48; CI95% = 1.30-4.74; P < 0.001)
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and eggs (OR = 3.04; CI95% = 1.51-6.15; P < 0.001) was linked to an increased risk of mouth and oropharyngeal cancer, in both the univariate and multivariate analyses. Among dairy products, milk showed a protective effect against the disease (OR = 0.41; CI95% = 0.21-0.82; P < 0.001).
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